Oleanolic Acid, Nordihydroguaiaretic Acid

(Osmotic gel)

Osmotic gel is a complex made of two ingredients: oleanolic acid, extracted from the leaves of the olive tree, and NDGA, the nordihydroguaiaretic acid.


The synergistic action of the two ingredients allows to fight acne on all fronts. Oleanolic acid inhibits 5-alpha-reductase, thus reducing sebum hypersecretion; nordihydroguaiaretic acid regulates cell growth, inhibiting hyperkeratosis and inflammation.


  • -44% seborrhoea after 6 weeks
  • -27% microcysts after 8 weeks
  • -35% comedones after 8 weeks
  • -32% pimples and pustules after 8 weeks
  • +35% improvement in the cutaneous conditions (self-assessment)

You can find this ingredient in the following products.